Aariva Pharma

HYDROCORTISONE ACETATE

CAS No.: 50-03-3

Chemical Formula: C23H32O6

General Information

Hydrocortisone acetate is a synthetic corticosteroid derived from cortisol, the body’s natural anti-inflammatory hormone. It is widely used in various pharmaceutical formulations for its anti-inflammatory, immunosuppressive, and anti-allergic properties. Hydrocortisone acetate acts by suppressing inflammatory responses, reducing swelling, and relieving itching associated with various skin conditions. It is available in different forms, including creams, ointments, lotions, and gels, catering to diverse dermatological needs.

Renowned for its safety profile, efficacy, and broad therapeutic range, hydrocortisone acetate is a trusted choice for healthcare professionals in the treatment of inflammatory skin disorders. Its significance extends beyond its chemical composition, impacting patient care and quality of life through effective symptom management.

Specifications

Hydrocortisone acetate typically presents as a white to off-white crystalline powder. It is sparingly soluble in water and exhibits a slightly bitter taste. The compound’s purity and particle size may vary depending on its intended use, ranging from pharmaceutical-grade to industrial-grade formulations. Hydrocortisone acetate conforms to regulatory standards for purity, safety, and potency, ensuring its suitability for dermatological applications.

Properties

  • White to off-white crystalline powder
  • Sparingly soluble in water
  • Slightly bitter taste
  • Anti-inflammatory, immunosuppressive, and anti-allergic properties
  • Meets pharmaceutical standards

Primary Functions

  • Treatment of inflammatory skin conditions

Applications

Hydrocortisone acetate is commonly prescribed for the management of various dermatological conditions, including eczema, dermatitis, psoriasis, and allergic reactions. It is available in different formulations, such as creams, ointments, lotions, and gels, allowing healthcare professionals to tailor treatment regimens to individual patient needs. Hydrocortisone acetate helps reduce inflammation, relieve itching, and promote skin healing, providing symptomatic relief and improving quality of life for patients.

Hydrocortisone acetate is applied topically to affected areas of the skin, where it exerts its anti-inflammatory and immunosuppressive effects locally. It is absorbed through the skin and acts directly on inflamed tissues, reducing redness, swelling, and discomfort. Hydrocortisone acetate is suitable for short-term and long-term use, depending on the severity and chronicity of the skin condition.

Hydrocortisone acetate may be used as adjuvant therapy in combination with other dermatological medications, such as antifungals, antibiotics, and moisturizers. It helps enhance the efficacy of concomitant treatments and improve overall treatment outcomes in patients with complex or refractory skin disorders.