Aariva Pharma

DEFLAZACORT

CAS No.: 14484-47-0

Chemical Formula: C25H31NO6

General Information

Deflazacort is a synthetic corticosteroid that is widely used in the treatment of inflammatory and autoimmune conditions affecting various organ systems. It belongs to the group of glucocorticoids and exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic properties. Deflazacort acts by suppressing inflammatory responses, reducing swelling, and modulating immune reactions associated with various medical conditions. It is available in oral tablet formulations, catering to diverse therapeutic needs.

Renowned for its efficacy, safety, and favorable pharmacokinetic profile, deflazacort is a preferred choice for healthcare professionals in the management of inflammatory diseases. Its significance extends beyond its chemical composition, impacting patient care and disease outcomes through effective symptom control and disease modification.

Specifications

Deflazacort typically presents as white to off-white crystalline powder. It is soluble in methanol and ethanol but sparingly soluble in water. The compound’s purity and particle size may vary depending on its intended use, ranging from pharmaceutical-grade to industrial-grade formulations. Deflazacort conforms to regulatory standards for purity, safety, and potency, ensuring its suitability for various medical applications.

Properties

  • White to off-white crystalline powder
  • Soluble in methanol and ethanol
  • Sparingly soluble in water
  • Potent anti-inflammatory, immunosuppressive, and anti-allergic properties
  • Meets pharmaceutical standards

Primary Functions

  • Treatment of inflammatory and allergic conditions

Applications

Deflazacort is indicated for the treatment of various autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus (SLE), and inflammatory bowel disease (IBD). It helps suppress inflammation, reduce pain, and improve organ function in patients with autoimmune conditions. Deflazacort may be used as monotherapy or in combination with other immunosuppressive medications to achieve disease remission and improve quality of life.

  • Deflazacort is prescribed for the management of severe allergic reactions, including anaphylaxis, angioedema, and allergic asthma exacerbations. It helps alleviate symptoms such as swelling, respiratory distress, and skin rash by suppressing allergic inflammation and immune reactions. Deflazacort is administered orally in emergency settings to rapidly control severe allergic symptoms and prevent complications.

Deflazacort is used for the treatment of various inflammatory conditions, including asthma, chronic obstructive pulmonary disease (COPD), and inflammatory skin disorders. It helps reduce airway inflammation, improve lung function, and alleviate symptoms of wheezing, coughing, and shortness of breath in patients with asthma and COPD. Deflazacort may also be used topically for the treatment of chronic skin conditions such as eczema and dermatitis, providing symptomatic relief and preventing disease flare-ups.