Aariva Pharma

CLOBETASOL PROPIONATE

CAS No.: 25122-46-7

Chemical Formula: C25H32ClFO5

General Information

Clobetasol propionate is a potent synthetic corticosteroid used in the treatment of various inflammatory and allergic skin disorders. It belongs to the group of glucocorticoids and exhibits strong anti-inflammatory, immunosuppressive, and vasoconstrictive properties. Clobetasol propionate acts by suppressing inflammatory responses, reducing swelling, and alleviating itching associated with dermatological conditions. It is available in different formulations, including creams, ointments, solutions, and foams, catering to diverse therapeutic needs.

Renowned for its high potency, efficacy, and rapid onset of action, clobetasol propionate is a preferred choice for healthcare professionals in the management of severe dermatoses. Its significance extends beyond its chemical composition, impacting patient care and quality of life through effective symptom control and disease modification.

Specifications

Clobetasol propionate typically presents as a white to creamy-white crystalline powder. It is practically insoluble in water but soluble in organic solvents. The compound’s purity and particle size may vary depending on its intended use, ranging from pharmaceutical-grade to industrial-grade formulations. Clobetasol propionate conforms to regulatory standards for purity, safety, and potency, ensuring its suitability for dermatological applications.

Properties

  • White to creamy-white crystalline powder
  • Practically insoluble in water
  • Soluble in organic solvents
  • Potent anti-inflammatory, immunosuppressive, and vasoconstrictive properties
  • Meets pharmaceutical standards

Primary Functions

  • Treatment of inflammatory and allergic skin conditions

Applications

Clobetasol propionate is indicated for the treatment of various severe inflammatory and allergic skin disorders, including psoriasis, eczema, lichen planus, and contact dermatitis. It is available in different formulations, such as creams, ointments, solutions, and foams, allowing healthcare professionals to tailor treatment regimens to individual patient needs. Clobetasol propionate helps reduce inflammation, relieve itching, and promote skin healing, providing rapid and effective symptomatic relief in patients with severe dermatoses.

Clobetasol propionate solution or foam is prescribed for the treatment of scalp conditions such as scalp psoriasis and seborrheic dermatitis. It helps reduce scalp inflammation, itching, and flaking associated with these conditions, providing relief and improving scalp health. Clobetasol propionate solution or foam is applied directly to the scalp, where it exerts its anti-inflammatory effects locally, providing symptomatic relief and preventing disease recurrence.