Aariva Pharma

CLOBETASOL BUTYRATE

CAS No.: 25122-57-0

Chemical Formula: C26H32ClFO5

General Information

Clobetasol butyrate is a potent synthetic corticosteroid used in the treatment of various inflammatory and allergic skin disorders. It belongs to the group of glucocorticoids and exhibits strong anti-inflammatory, immunosuppressive, and vasoconstrictive properties. Clobetasol butyrate acts by suppressing inflammatory responses, reducing swelling, and alleviating itching associated with dermatological conditions. It is available in different formulations, including creams, ointments, and lotions, catering to diverse therapeutic needs.

Renowned for its high potency, efficacy, and rapid onset of action, clobetasol butyrate is a preferred choice for healthcare professionals in the management of moderate to severe dermatoses. Its significance extends beyond its chemical composition, impacting patient care and quality of life through effective symptom control and disease modification.

Specifications

Clobetasol butyrate typically presents as a white to creamy-white crystalline powder. It is practically insoluble in water but soluble in organic solvents. The compound’s purity and particle size may vary depending on its intended use, ranging from pharmaceutical-grade to industrial-grade formulations. Clobetasol butyrate conforms to regulatory standards for purity, safety, and potency, ensuring its suitability for dermatological applications.

Properties

  • White to creamy-white crystalline powder
  • Practically insoluble in water
  • Soluble in organic solvents
  • Potent anti-inflammatory, immunosuppressive, and vasoconstrictive properties
  • Meets pharmaceutical standards

Primary Functions

  • Treatment of inflammatory and allergic skin conditions

Applications

Clobetasol butyrate is indicated for the treatment of various moderate to severe inflammatory and allergic skin disorders, including eczema, dermatitis, and psoriasis. It is available in different formulations, such as creams, ointments, and lotions, allowing healthcare professionals to tailor treatment regimens to individual patient needs. Clobetasol butyrate helps reduce inflammation, relieve itching, and promote skin healing, providing rapid and effective symptomatic relief in patients with moderate to severe dermatoses.

Clobetasol butyrate may be used for the long-term management of chronic inflammatory skin conditions such as lichen planus and discoid lupus erythematosus. It helps control disease activity, prevent flare-ups, and improve quality of life in patients with chronic dermatoses. Clobetasol butyrate is applied topically to affected areas of the skin, where it exerts its anti-inflammatory effects locally, providing sustained relief and disease control.

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